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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICK
All Species:
20.91
Human Site:
Y473
Identified Species:
41.82
UniProt:
Q9UPZ9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPZ9
NP_055735.1
632
71427
Y473
S
A
P
T
Q
T
S
Y
Q
R
R
D
T
P
T
Chimpanzee
Pan troglodytes
XP_001154965
633
71532
Y474
S
A
P
T
Q
T
S
Y
Q
R
R
D
T
P
T
Rhesus Macaque
Macaca mulatta
XP_001100720
616
68399
Y457
S
A
P
T
Q
M
S
Y
Q
R
R
D
T
P
T
Dog
Lupus familis
XP_538964
685
76968
Y526
S
A
P
T
Q
T
S
Y
Q
R
R
D
T
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV2
629
70573
S470
T
V
S
T
Q
A
S
S
Q
R
R
D
T
P
T
Rat
Rattus norvegicus
Q62726
629
70550
S470
S
V
S
T
Q
A
S
S
Q
R
R
D
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514373
624
70740
T467
G
A
F
L
K
N
D
T
D
L
S
T
A
S
T
Chicken
Gallus gallus
Frog
Xenopus laevis
P23437
297
33852
I141
L
I
N
S
D
G
A
I
K
L
A
D
F
G
L
Zebra Danio
Brachydanio rerio
NP_956240
633
71283
Q473
G
L
I
S
K
N
T
Q
S
L
S
S
K
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392924
569
65790
W413
L
P
E
N
P
R
N
W
V
L
P
A
W
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200813
576
64528
K420
K
I
G
G
M
K
G
K
A
L
P
T
I
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
L286
R
P
T
A
D
E
A
L
N
H
P
F
F
S
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
86.8
86.1
N.A.
86.3
85.5
N.A.
56.6
N.A.
23.1
47
N.A.
N.A.
45.8
N.A.
48.5
Protein Similarity:
100
99.5
90
89.4
N.A.
92
91.6
N.A.
68.8
N.A.
32.1
60.5
N.A.
N.A.
61.3
N.A.
62.1
P-Site Identity:
100
100
93.3
100
N.A.
66.6
73.3
N.A.
13.3
N.A.
6.6
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
73.3
73.3
N.A.
20
N.A.
26.6
26.6
N.A.
N.A.
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
9
0
17
17
0
9
0
9
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
9
0
9
0
0
59
0
0
0
% D
% Glu:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
9
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
9
17
0
0
% F
% Gly:
17
0
9
9
0
9
9
0
0
0
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
17
9
0
0
0
0
9
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
17
9
0
9
9
0
0
0
9
0
0
% K
% Leu:
17
9
0
9
0
0
0
9
0
42
0
0
0
0
9
% L
% Met:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
9
0
17
9
0
9
0
0
0
0
9
0
% N
% Pro:
0
17
34
0
9
0
0
0
0
0
25
0
0
50
0
% P
% Gln:
0
0
0
0
50
0
0
9
50
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
9
0
0
0
50
50
0
0
0
0
% R
% Ser:
42
0
17
17
0
0
50
17
9
0
17
9
0
17
9
% S
% Thr:
9
0
9
50
0
25
9
9
0
0
0
17
50
0
59
% T
% Val:
0
17
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _